Can I Stop Trazodone Cold Turkey?

Trazodone is an antidepressant primarily indicated for use in treating major depressive disorder but perhaps more commonly used off-label for managing insomnia. As an atypical antidepressant, trazodone does not fit neatly into some of the more standard antidepressant classes (e.g., SSRIs, MAOIs, tricyclic antidepressants, etc.).

Like most medications, trazodone use may have side effects, and long-term use can result in trazadone withdrawal, if a person suddenly attempts to stop or cutback on their use. Read on to learn more about the potential side effects of trazodone use, withdrawal symptoms, and treatment options for prescription drug addiction.

Trazodone is an antidepressant medication that is often prescribed to treat depression and insomnia. It works by increasing levels of serotonin in the brain, which can improve mood and promote sleep.

While trazodone can be very helpful for many people, some may eventually decide they want to stop taking it. Quitting trazodone abruptly or “cold turkey” is possible but it’s not recommended. Stopping trazodone suddenly can cause uncomfortable withdrawal symptoms.

To safely discontinue trazodone, it’s best to taper off the medication gradually under the supervision of your doctor. This method can minimize or avoid withdrawal effects.

What Happens When You Quit Trazodone Cold Turkey?

When you stop taking trazodone suddenly, your brain is no longer getting the extra serotonin boost it had adapted to This abrupt drop in serotonin can cause both physical and psychological withdrawal symptoms

Common trazodone withdrawal symptoms include:

  • Headache
  • Nausea
  • Dizziness
  • Fatigue
  • Insomnia or vivid dreams
  • Irritability
  • Anxiety
  • Sweating
  • Sensory disturbances

The severity of withdrawal can vary significantly from person to person. Those who were on higher doses of trazodone for longer periods of time tend to have more intense symptoms.

Withdrawal symptoms from quitting trazodone cold turkey usually begin within a couple days after the last dose. Certain symptoms like insomnia and mood swings may persist for weeks or longer as the brain readjusts.

In rare cases, abruptly stopping antidepressants like trazodone can also cause more serious side effects. These include suicidal thoughts, mania, psychosis, and seizures.

While trazodone withdrawal is not normally dangerous, the discomfort and risks make suddenly quitting this medication inadvisable. A supervised taper is the safest way to wean off trazodone.

Is Trazodone Addictive?

Trazodone is not considered addictive when taken as prescribed by a doctor. However, it does carry a risk of dependence, which means stopping the medication abruptly can cause withdrawal symptoms.

The difference between addiction and dependence is subtle but important. Addiction involves compulsive drug-seeking behavior despite negative consequences. Dependence means the body has adapted to the drug such that abruptly stopping it leads to symptoms of withdrawal.

People taking trazodone as prescribed do not exhibit drug cravings or compulsive use typical of addiction. But they may become dependent on the serotonin effects, making discontinuation uncomfortable without tapering.

It’s also possible to develop a psychological dependence on trazodone’s sleep-promoting qualities. Those who rely on it for insomnia may have rebound insomnia when first quitting. However, this sleep disturbance is temporary and should not be mistaken for physiological addiction.

Tapering Off Trazodone Slowly

To minimize the risk of withdrawal symptoms, doctors recommend gradually tapering trazodone over a period of weeks or months. This gives your brain more time to adapt to each dose reduction.

There is no single best tapering schedule that works for everyone. Your doctor will tailor the weaning plan and timeline based on factors like:

  • Your current trazodone dosage
  • How long you’ve taken trazodone
  • Your history of withdrawal sensitivity
  • The severity of your underlying condition

A typical trazodone taper may involve decreasing your dosage by 25-50 mg every 1-2 weeks. However, slower schedules over several months are often better tolerated, especially if you’ve taken trazodone for a long time.

Your doctor may temporarily switch you to a liquid formulation toward the end to allow smaller dose reductions. Some people take their last doses every 2-3 days instead of daily at the end of the taper.

Sometimes dosage adjustments are necessary if withdrawal symptoms become too severe during the tapering process. The goal is to proceed slowly enough to minimize discomfort. Patience is key to success, as forcing the process increases withdrawal risk.

What to Expect When Tapering Trazodone

Tapering off trazodone gradually can reduce the severity of withdrawal effects. However, some symptoms are still possible during the weaning process.

Insomnia, vivid dreams, anxiety, irritability, and headache are among the most commonly reported symptoms during a trazodone taper. Fatigue and brain fog are also frequent complaints.

Such withdrawal effects tend to come and go in waves, often worsening for a few days after each dosage reduction. Staying busy and utilizing stress management techniques can help cope with any discomfort.

Symptoms may temporarily improve at points during the taper, only to return days or weeks later. Mood instability, digestion problems, and sensory disturbances can arise even toward the end. Patience and close monitoring are vital.

With slow trazodone discontinuation, withdrawal symptoms are usually mild to moderate in intensity. However, each person’s experience is unique based on individual biology and dosage effects. Don’t hesitate to seek medical advice if struggling.

Seeking Help for Trazodone Withdrawal

Quitting trazodone cold turkey is strongly discouraged. But even with tapering, you may encounter challenging withdrawal symptoms. In these cases, don’t hesitate to seek medical advice and support.

Your prescribing doctor can help adjust your tapering plan if you are having intolerable side effects. Temporary use of other medications may ease specific withdrawal symptoms that emerge.

Counseling can also help some people cope with the emotional aspects of discontinuing trazodone. Support groups connect you with others who understand the process.

Getting adequate rest, nutrition, and exercise is important during withdrawal. Reduce stress where possible and ask loved ones for help with daily responsibilities when needed.

Most symptoms resolve within a few weeks to months after finishing the taper. But the timeline varies, so be patient and focus on overall health during this transition. Contact emergency services if you have suicidal thoughts or other dangerous symptoms.

Can I Restart Trazodone After Quitting?

Some people wish to restart trazodone after completing withdrawal, whether due to lingering symptoms or the return of the original condition. This is generally safe, though dosage adjustments may be required.

If you tapered off trazodone successfully but the underlying condition returned, your doctor may prescribe trazodone again using the lowest effective dose. This reintroduction phase aims to avoid dependence.

Should withdrawal symptoms persist longer than expected, briefly restarting trazodone may provide relief. Discuss the optimal duration with your doctor to avoid prolonged use.

However, if trazodone caused serious side effects or addiction tendencies, it may be best avoided. Other medication options or non-drug therapies should be explored first in such cases.

Is There an Easier Way to Quit Trazodone?

While no magic shortcut exists to eliminate trazodone withdrawal, some strategies can help ease the process:

  • Ask about switching to fluoxetine near the end of tapering since its long half-life provides a more gradual transition.

  • Take your last few smaller doses every 2-3 days instead of daily to minimize dips.

  • Adopt healthy stress-relieving habits like meditation, light exercise, and sufficient sleep.

  • Stay busy and maintain a structured schedule to take your mind off symptoms.

  • Join a support group to exchange tips and encouragement with others.

  • Consider short-term medications to relieve specific severe symptoms if tapering becomes intolerable.

  • Communicate regularly with your doctor and ask questions. They can adjust the taper plan if you struggle.

  • Be patient with yourself and understand temporary discomfort is normal when withdrawing from any antidepressant.

The bottom line is there are no shortcuts around the gradual taper process. Working closely with your doctor and utilizing healthy coping strategies will make quitting trazodone easier to handle. The payoff of getting through withdrawal is regaining your health and independence.

While trazodone is not addictive in the strict sense, stopping it abruptly can cause difficult withdrawal symptoms. To avoid this, doctors recommend gradually weaning off trazodone over weeks or months.

Quitting trazodone cold turkey is possible but not advisable. The best approach for most people is following a slow medication taper under medical supervision. This minimizes discomfort and safely transitions the brain back to normal functioning.

Have patience during the trazodone withdrawal process. Communicate with your doctor if you struggle with tapering or have concerns about your progress. They can adjust your plan and offer support. Most symptoms do resolve with time after completing the weaning schedule.

can i stop trazodone cold turkey

What Happens If You Take Too Much Trazodone?

Taking too much trazodone at one time can be dangerous. Trazodone overdose symptoms include:

  • Hypotension (low blood pressure that may result in fainting).
  • Chest pain.
  • Trouble breathing.
  • Drowsiness.
  • Tremor.
  • Cardiac arrhythmias.
  • Seizures.
  • Coma.

Learn More about the risks of a trazodone overdose.

While most people don’t misuse trazodone, it does happen. Due to the fact that the abuse potential of trazodone is relatively low, it is difficult to find any legitimate information about signs of trazodone addiction. However, if you are concerned about your or a loved one’s trazodone use, some of the general signs of prescription drug misuse are:

  • Taking the drug in a dose other than what is prescribed.
  • Taking someone else’s prescription.
  • Taking the drug in ways other than prescribed.
  • Taking the drug to feel pleasurable side effects, such as euphoria or sedation.

If you are worried about your prescription drug use but need to manage symptoms of depression, anxiety, and insomnia, Greenhouse Treatment Center can help. Our licensed clinical team specializes in co-occurring disorders, treating patients’ mental and behavioral health conditions alongside substance use disorder.

Our compassionate team cares about treating the whole person, not just their drug use. If you’d like to learn more about treatment options for you or someone you know, call us at today.

According to an article in the Journal of Clinical Psychiatry, trazodone is thought to have a lower abuse liability than benzodiazepines like triazolam or other hypnotics prescribed for insomnia, which may be why its off-label use for the treatment of insomnia has surpassed its use for the management of major depression.

Trazodone Side Effects & Risks of Use

Trazodone use may have certain side effects. The most common adverse reactions include:

  • Drowsiness.
  • Dizziness.
  • Headaches.
  • Constipation.
  • Blurred vision.

While these symptoms are relatively mild, trazodone use can, in rare cases, can cause more serious side effects. It is important to note the warnings and risks associated with trazodone use before you take it. These include:

  • A slight risk of serotonin syndrome, a potentially fatal condition characterized by changes in mental status, as well as neuromuscular and autonomic hyperactivity.
  • Heart rhythm abnormalities. Patients with underlying cardiac conditions should discuss the risks of trazodone with their physicians.
  • Orthostatic hypotension (drop in blood pressure upon standing) and fainting.
  • Prolonged, painful erections (priapism) in some males.
  • Abnormal bleeding, especially when combined with NSAIDs, such as aspirin and ibuprofen.
  • Activation of mania/hypomania states, among patients with bipolar disorder.
  • Worsened symptoms of depression and increased risk of suicidal thinking or behaviors.

These warnings apply to individuals taking trazodone as prescribed. Abuse of the drug may make an individual more likely to experience one or more of the above issues.

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FAQ

Can trazodone be stopped abruptly?

Because withdrawal symptoms from trazodone can be uncomfortable and may occur when someone suddenly stops taking the drug, doctors generally recommend that a person slowly taper or gradually reduce the medication’s dosage over a period of weeks to months.

Does trazodone need to be tapered?

Trazodone may cause a discontinuation syndrome if abruptly stopped, symptoms include anxiety, agitation, and sleep disturbances. When the time comes to withdraw trazodone, the dosage should be tapered off slowly under a doctor’s advice.

What happens if you take trazodone every night?

It is not uncommon for trazodone to be prescribed daily and to be taken in the evening. However, if a person is misusing trazodone, taking it every night can be extremely harmful, increase the risk of overdose, and have serious negative effects on their physical and mental health.

How long does it take for trazodone to wear off?

Trazodone’s half-life, or the time it takes for the body to eliminate half of the drug, typically ranges from 5 to 9 hours. However, this can vary depending on individual factors such as age, metabolism, liver function, and the presence of other medications.

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