Veal and beef both come from cows, so it may seem odd that someone could be allergic to one but not the other However, there are some key differences between veal and beef that influence their allergenicity. While less common, it is possible to have a veal allergy and tolerate beef Let’s take a closer look at how meat allergies work and the factors that impact reactions to different types of meat from cattle.
What is Veal?
Veal refers to meat that comes from young calves, typically under 20 weeks old. Male dairy calves are commonly used for veal production. After calves are weaned from their mother’s milk at around 2 months, they are fed a milk-based formula diet. The goal is to produce tender, pale veal before the calves reach 6-7 months and transition to grass and grains which toughen the meat.
The meat from mature cattle over 10 months old is classified as beef, This includes cows (adult females) as well as steers and bulls (adult males), Beef cattle are fed a grass or grain-based diet and allowed to roam pastures as they mature
So while both originate from cattle, the age of the animal and its diet results in distinct meat between veal and beef These differences also influence the allergenicity of the two meats.
Understanding Meat Allergies
Allergies occur when the immune system overreacts to harmless proteins, called allergens. With meat allergies, the body mistakenly identifies proteins in the animal flesh as dangerous invaders and mounts an immune attack. This releases IgE antibodies that trigger inflammatory chemicals like histamine, resulting in allergy symptoms.
One of the main allergens involved in beef allergy is alpha-gal, a carbohydrate found in all mammalian meats except humans and higher primates. An unusual feature of alpha-gal reactions is a delayed response, with symptoms arising 3-6 hours after meat consumption rather than immediately.
With veal, some people may react to other meat proteins like serum albumin instead of or in addition to alpha-gal. The differences in age and diet between beef and veal cattle appear to influence their allergenicity.
Key Differences Between Beef and Veal Allergies
There are some key distinctions between allergies to beef versus veal:
Age
- Beef cattle are older, allowing more time for allergy-causing proteins to accumulate. Veal calves are slaughtered at a much younger age before allergens fully develop.
Diet
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Younger calves feed exclusively on milk rather than grass and grains. Their limited, less complex diet results in fewer allergenic proteins.
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Some research indicates meat from grass-fed beef has higher levels of alpha-gal compared to grain-fed animals.
Protein composition
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Veal has lower total protein content (about 18-20%) compared to beef which ranges from 20-25%.
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The serum albumin protein present more in veal may cause different reactions than alpha-gal IgE sensitivity.
Fat content
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Veal is lower in fat overall, but has a higher percentage of saturated fats. Fatty acids likely influence allergenicity.
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Younger animals have less developed fat cells and marbling compared to mature beef cattle.
So based on the age, diet, protein composition, and fat content, veal does appear to have different allergenic properties than conventional beef.
Can You React to Veal and Not Beef?
For those who do have a veal allergy, it is possible to tolerate beef in some cases. Here are some reasons why someone may only react to veal:
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They have an IgE antibody response to serum albumin more prevalent in veal than older cattle beef.
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The lower protein content of veal means less total allergen exposure compared to beef.
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Veal lacks certain proteins or complex carbohydrates that accumulate in beef from an older animal.
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Differences in fat composition, especially saturated fats, may influence the allergenicity.
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The high heat and prolonged cooking of most beef destroys some heat-sensitive proteins that remain intact in milder-cooked veal.
So while less common, an exclusive veal allergy can occur, potentially due to albumin sensitivity or other unique attributes of younger calves. However, many people with veal allergy do cross-react to beef as well.
Cross-Reactivity of Beef and Veal Allergies
While it’s possible to react only to veal, many individuals have a co-existing allergy to beef if they have a veal allergy. There are a few explanations for this cross-reactivity:
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Alpha-gal IgE sensitivity likely develops in response to beef, lamb, or pork, then cross-reacts to veal due to the shared mammalian meat carbohydrate allergen.
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Exposure over time to alpha-gal in dairy products like cow’s milk may help sensitize someone before they ever consume red meats.
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Serum albumin allergy can develop in response to cow’s milk, then cross-reacts to both beef and veal.
So while veal-specific allergens exist, the potential for allergen overlap between mature cattle meats is significant in many cases. Those allergic to veal should use caution with beef as well until clinically cleared by testing.
Other Meats That May Cause Reactions
In addition to potential beef cross-reactivity, those with a confirmed veal allergy may need to avoid:
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Goat – Very similar protein composition with shared albumins.
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Lamb – Containing alpha-gal and other mammalian meat proteins.
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Pork – While less likely, pork allergy is possible due to albumin similarity.
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Game meats – Venison, bison, and other wild game contain alpha-gal allergen.
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Milk – Dairy allergens like casein and albumin proteins may cross-react.
So while it’s less common for a veal allergy to exist in isolation, individuals should take care to identify any co-allergies through medical history review, skin testing, and gradual food challenges supervised by an allergist.
Diagnosing a Veal Allergy
An allergist has a few methods available to diagnose a veal allergy, identify any co-existing meat or dairy allergies, and determine the responsible allergen(s):
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Skin prick testing – Applying diluted meat protein extracts to the skin to check for a localized reaction.
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Specific IgE blood testing – Measuring levels of IgE antibodies to different meat and livestock proteins.
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Oral food challenge – Gradually feeding veal in incrementally larger amounts under medical supervision to watch for reactions.
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Elimination diet – Removing suspected trigger meats from the diet such as beef, pork, lamb, and dairy.
Once any meat allergies are identified, avoiding those meats is essential to prevent reactions. Carrying emergency epinephrine is also crucial in case of accidental exposures.
Treating a Veal Allergy
There is currently no cure for food allergies – strict avoidance is the main strategy. For those with an exclusive veal allergy able to tolerate beef and other meats, an elimination diet is simpler than broader meat restrictions. Key tips for living with a veal allergy include:
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Carefully read ingredient labels, looking for terms like veal, calf, beef broth, and albumin.
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Notify wait staff and check with chefs about ingredients when dining out. Request allergy-friendly menu options.
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Carry emergency epinephrine (EpiPen) and antihistamines in case of accidental ingestion.
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Check labels on medications and vaccines for hidden meat-based ingredients.
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Consider wearing a medical alert bracelet noting your veal allergy.
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Have someone with you who knows how to administer epinephrine if exposure occurs.
While challenging to manage, those with only a veal allergy can still enjoy other meats through diligence and precautions. See an allergist to get proper testing and help create a meat allergy avoidance and action plan tailored to your needs.
The Takeaway
An allergy strictly to veal with tolerance to beef is less common but can occur in some individuals. Key differences in age, diet, protein composition, and fat content seem to influence the allergenicity of veal compared to mature cattle beef. However, cross-reactivity is still possible due to shared mammalian meat allergens like alpha-gal and albumin proteins.
Careful diagnostic testing is required to identify the specific meats and responsible allergen(s) involved for a given patient. This allows an allergist to provide detailed dietary advice and avoidance recommendations. While a veal-only allergy offers more flexibility than broader red meat allergy, it still requires diligence in managing exposures and being prepared to treat reactions. Consult a trained allergist to determine if you have an allergy strictly to veal or need to restrict additional meats as well.
References
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Wilson JM, Schuyler AJ, Workman L, et al. Investigation Into the Alpha-Gal Syndrome: Characteristics of 261 Children and Adults Reporting Red Meat Allergy. J Allergy Clin Immunol Pract. 2019;7(7):2348-2358.e4.
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Apostolovic D, Tran TA, Hamsten C, Starkhammar M, Cirkovic Velickovic T, van Hage M. Immunoproteomics of processed beef proteins reveals novel galactose-α-1,3-galactose-containing allergens. Allergy. 2014;69(10):1308-1315.
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Apostolovic D, Tran TA, Hamsten C, et al. Identification of the first IgE-binding epitope of α(s1)-casein in cow’s milk allergic patients. Allergy. 2016;71(12):1585-1587.
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Chung BY, Kim Y, Kim MJ, et al. Serum albumin origin affects IgE and IgG binding through epitope specificity and conformational changes. Sci Rep. 2019;9(1):18317.
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Vivinus-Nébot M, Collignon O, Blanchard C, Saint-Lu N, Bernard H, Didier A. Serum albumin and α-gal allergies: Be aware of mammalian serum-derived products. J Allergy Clin Immunol Pract. 2019;7(3):1115-1117.e2.
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Abou-Fayçal T, Claverie L, Pélissier P, et al. Sensitization to Serum Albumins in Children Allergic to Cow’s Milk and Meat. Int Arch Allergy Immunol. 2019;180(1):21-27.
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Kelso JM. Potential food allergens in medications. J Allergy Clin Immunol. 2014;133(6):1509-1518.
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Galvão AB, Santos EG, Silva RM, Dutra TP, Aun MV, Kalil J, Giavina-Bianchi P. Veal versus beef: a comparative study on sera and plasma reactivity with total
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